Modelling mixed culture fermentations; the role of different electron carriers

Jorge Rodriguez-Rodriguez, M. F. Temudo, M.C.M. van Loosdrecht, R. Kleerebezem

Research output: Contribution to journalArticlepeer-review


A recently established mixed culture fermentation (MCF) model has been modified to account for the role of different electron carriers in the process. The MCF-model predicts the product spectrum as a function of the actual environmental conditions using a thermodynamic optimization criterion while satisfying a number of constrants. Other improvements made to the original model are the inclusion of formate as fermentation end-product, and gas-liquid mass transfer. The model is adequately capable of reproducing experimental results in terms of butyrate and formate versus hydrogen/carbon dioxide production. The model is not capable of predicting the production of an ethanol/acetate mixtue as measured at higher pH-values, suggesting specific biochemical control. Catabolic acetate production can potentially be explained by anabolic requirements for a specific electron donor like NADH.
Original languageEnglish
Pages (from-to)493 - 497
Number of pages4
JournalWater Science and Technology
Issue number4
Publication statusPublished - 1 Jan 2008


  • acidogenesis
  • electron carrier
  • fermentation
  • mathematical model


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