Nonparametric population modeling and Bayesian analysis.

Tatiana Tatarinova, Roger Jelliffe, Michael Neely, Alan Schumitzky, David Bayard, Michael Van Guilder, Andreas Botnen, Aida Bustad, Derek Laing, Walter Yamada, Jay Bartroff

Research output: Contribution to journalArticlepeer-review


The nonparametric (NP) population modeling approach estimated the model parameter values and predicted the observed mycophenolic acid concentrations more precisely than the parametric method did. We expect this because the NP method makes no assumptions about the shape of the model parameter distributions, as parametric methods do, and therefore obtains results that are more likely given the data.
Original languageEnglish
JournalPharmacological Research
Issue number4
Publication statusE-pub ahead of print - 23 Apr 2011


  • pharmacokinetics


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