Tibolone and climacteric symptoms

Linda Ross, Elisabeth Alder

Research output: Contribution to journalArticlepeer-review


Tibolone (Livial) has advantages over other forms of hormone replacement therapy (HRT); it is easy to use and does not induce withdrawal bleeding in postmenopausal women. The evidence for the effect of tibolone on climacteric symptoms is reviewed and shows that tibolone is effective in reducing vasomotor symptoms and vaginal dryness. Tibolone's effect on a range of other symptoms such as headache and insomnia is unclear. There are reports that tibolone improves mood and libido but much of this research is methodologically flawed. Methodologically sound research is required to investigate tibolone's effect on mood and libido; such a study is in progress.
Original languageEnglish
Pages (from-to)127-136
Number of pages10
Issue number2
Publication statusPublished - 1995


  • Tibolone
  • Livial
  • Climacteric symptoms
  • Psychological symptoms


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